Hirschsprung Disease

Hirschsprung disease is characterized by a congenital absence of ganglion cells in the distal colon resulting in a functional obstruction. Although this condition was described by Ruysch in 1691 and popularized by Hirschsprung in 1886, the pathophysiology was not clearly determined until the work of Swenson in the middle of the 20th century.

Most cases of Hirschsprung disease are now diagnosed in the newborn period. Hirschsprung disease should be considered in any newborn who fails to pass meconium within 24-48 hours after birth. Although contrast enema is useful in establishing the diagnosis, rectal biopsy remains the criterion standard. Once the diagnosis is confirmed, the basic treatment is to remove the poorly functioning aganglionic bowel and create an anastomosis to the distal rectum with the healthy innervated bowel (with or without an initial diversion).

I pray that my son does not have this. I hope he poops on his own soon.